Humoral immunity and cell-mediated immunity are the two branches of adaptive immunityHumoral immunity is a B-cell and antibody-mediated response directed against extracellular microbial pathogens especially encapsulated bacteria certain intracellular microbial pathogens viruses and microbial toxins. Importantly the risk of influenza disease was comparable in elderly demonstrating a cell-mediated response alone an antibody response alone or both cell-mediated and antibody. Humoral Vs Cell Mediated Immunity Similarities And Differences Hematopoietic Stem Cell Transplantation Autoimmune Disease Stem Cells The sera were subjected to neutralization and antibody-dependent cell-mediated cytotoxicity ADCC tests. . The humoral response or antibodymediated response involves B cells that recognize antigens or pathogens that are circulating in the lymph or blood humor is a medieval term for body fluid. Comparison between humoral and cell-mediated immu